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CS-W001157 4
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Di([1,1'-biphenyl]-4-yl)methanone

  • CAS No. 3478-90-8

  • Cat. No. CS-0332699
  • Molecule weight334.41
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Di([1,1'-biphenyl]-4-yl)methanone|CS-0332699

Structure of 3478-90-8

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General Information

  • CAS No. 3478-90-8
  • Cat. No. CS-0332699
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₅H₁₈O
  • Molecular Weight 334.41
  • Synonym(s) Di-4-biphenylyl ketone
  • SMILES C1=CC=C(C=C1)C2=CC=C(C=C2)C(=O)C3=CC=C(C=C3)C4=CC=CC=C4

Description

Di([1,1'-biphenyl]-4-yl)methanone features a rigid, electron-rich biphenyl scaffold that enhances π-stacking interactions in supramolecular assemblies. This sterically defined ketone integrates readily into conjugated frameworks for materials applications, offering robust stability under standard handling conditions.

Application

Di([1,1'-biphenyl]-4-yl)methanone serves as a robust aryl ketone building block for the construction of biaryl-containing scaffolds in medicinal chemistry and materials science. Its stability under standard reaction conditions enables reliable use in Suzuki-Miyaura coupling, Friedel-Crafts acylation, and nucleophilic addition reactions. The molecule's defined steric profile and functional group tolerance facilitate efficient synthesis of complex architectures with predictable reactivity.

Synthesis

  • Route1

    References

    • Bolliger, Jeanne L.; Frech, Christian M. Chemistry - A European Journal, 2010 , vol. 16, # 13 p. 4075 - 4081
  • Route2
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      4596-95-6
    • ~%
    • In-stock
      Di([1,1'-biphenyl]-4-yl)methanone|CS-0332699
      3478-90-8

    References

    • Archiv der Pharmazie und Berichte der Deutschen Pharmazeutischen Gesellschaft, , vol. 293, p. 127 - 132
  • Route3
    • null|null
      79-37-8
    • null|null
      92-52-4
    • ~%
    • In-stock
      Di([1,1'-biphenyl]-4-yl)methanone|CS-0332699
      3478-90-8
    • In-stock
      Bis(4-phenylphenyl)ethane-1,2-dione|CS-0220783
      4746-80-9

    References

    • Journal of the American Chemical Society, , vol. 56, p. 2429

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS03,GHS06,GHS08,GHS09
Signal Word : Danger
UN#: 1479
Class : 5.1
Packing Group : Ⅲ
Hazard Statements : H271-H301+H311+H331-H350-H410
Precautionary Statements : P210-P220-P261-P264-P270-P271-P273-P280-P283-P302+P352-P304+P340-P306+P360-P330-P361+P364-P370+P378-P391-P405-P420-P501

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Computational Chemistry Data

  • TPSA   17.07
  • LogP   6.2516
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   4

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