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CS-W001157 4
Total: USD 88.00

5-Oxo-5,6,7,8-tetrahydronaphthalene-2-carboxylic acid

  • CAS No. 3470-46-0

  • Cat. No. CS-W019165
  • Purity≥95%
  • MDL No.MFCD01763813
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

5-Oxo-5,6,7,8-tetrahydronaphthalene-2-carboxylic acid|CS-W019165

Structure of 3470-46-0

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Description

This tetrahydronaphthalene carboxylic acid features a conjugated enone system and a carboxylate group, enabling direct integration into synthetic routes for bioactive heterocycles. The electron-deficient ring facilitates nucleophilic additions and Diels-Alder reactions under mild conditions. Bench-stable and moisture-tolerant, it serves as a versatile scaffold in medicinal chemistry and materials synthesis.

Application

5-Oxo-5,6,7,8-tetrahydronaphthalene-2-carboxylic acid serves as a versatile scaffold for the synthesis of substituted naphthalene derivatives and heterocyclic systems. Its fused bicyclic structure provides rigidity and defined stereochemistry, while the carboxylic acid and ketone functionalities enable diverse transformations including amidation, esterification, and nucleophilic addition. The compound exhibits good bench stability and facilitates straightforward purification, making it suitable for use in medicinal chemistry campaigns and process development.

General Information

  • CAS No. 3470-46-0
  • Cat. No. CS-W019165
  • Purity ≥95%
  • MDL No. MFCD01763813
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₀O₃
  • Molecular Weight 190.20
  • Synonym(s) 6-Carboxy-1-oxo-1,2,3,4-tetrahydronaphthalene, 5-Oxo-5,6,7,8-tetrahydro-2-naphthoic acid
  • SMILES OC(=O)C1=CC2=C(C=C1)C(=O)CCC2

Computational Chemistry Data

  • TPSA   54.37
  • LogP   1.9038
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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