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CS-W001157 4
Total: USD 88.00

2,7-Dimethoxynaphthalene

  • CAS No. 3469-26-9

  • Cat. No. CS-M0858
  • Purity≥98%
  • MDL No.MFCD00004064

*For research and further manufacturing use only, not for direct human use.

2,7-Dimethoxynaphthalene|CS-M0858

Structure of 3469-26-9

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General Information

  • CAS No. 3469-26-9
  • Cat. No. CS-M0858
  • Purity ≥98%
  • MDL No. MFCD00004064
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₂O₂
  • Molecular Weight 188.22
  • Synonym(s) 2,7-dimethoxyl Naphthalene
  • SMILES COC1=CC2=CC(OC)=CC=C2C=C1

Description

2,7-Dimethoxynaphthalene was employed as matrix to investigate the structure of polymetallic porphyrins via matrix-assisted laser desorption/ionization. It was also used in the synthesis of:peri-aroylnaphthalene compounds via elective electrophilic aromatic aroylation2-amino-1,2,3,4-tetrahydronaphthalene-6,7-diol

Application

2,7-Dimethoxynaphthalene serves as a valuable building block in synthetic organic chemistry, offering enhanced solubility and stability compared to unsubstituted naphthalenes. The ortho-dimethoxy substitution pattern facilitates electrophilic aromatic substitution at C4 and C5 positions, enabling efficient functionalization for advanced intermediates in pharmaceutical and agrochemical synthesis. Its bench-stable nature and compatibility with standard coupling reactions make it a practical choice for multi-step syntheses.

Synthesis

  • Route1
    • null|null
      93750-00-6
    • null|null
      77-78-1
    • ~3%
    • In-stock
      2,7-Dimethoxynaphthalene|CS-M0858
      3469-26-9
    • null|null
      108189-49-7

    References

    • Journal of the American Chemical Society, , vol. 109, p. 3174
  • Route2
    • In-stock
      2,7-Dihydroxynaphthalene|CS-W016167
      582-17-2
    • null|null
      74-88-4
    • ~65%
    • In-stock
      2,7-Dimethoxynaphthalene|CS-M0858
      3469-26-9

    References

    • Kuhnert, Nikolai; Burzlaff, Nicolai; Patel, Chirag; Lopez-Periago, Ana Organic and Biomolecular Chemistry, 2005 , vol. 3, # 10 p. 1911 - 1921
  • Route3
    • In-stock
      2,7-Dihydroxynaphthalene|CS-W016167
      582-17-2
    • null|null
      77-78-1
    • ~98%
    • In-stock
      2,7-Dimethoxynaphthalene|CS-M0858
      3469-26-9

    References

    • Domasevitch, Konstantin V.; Solntsev, Pavlo V.; Krautscheid, Harald; Zhylenko, Iryna S.; Rusanov, Eduard B.; Chernega, Alexander N. Chemical Communications, 2012 , vol. 48, # 47 p. 5847 - 5849

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335-H401
Precautionary Statements : P261-P264-P271-P273-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   18.46
  • LogP   2.857
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   2

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