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CS-W001157 4
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rel-(1r,2R,3S)-2,3-Dimethylcyclopropane-1-carboxylic acid

  • CAS No. 34669-51-7

  • Cat. No. CS-0614190
  • Purity≥98%
  • MDL No.MFCD19228817

*For research and further manufacturing use only, not for direct human use.

rel-(1r,2R,3S)-2,3-Dimethylcyclopropane-1-carboxylic acid|CS-0614190

Structure of 34669-51-7

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General Information

  • CAS No. 34669-51-7
  • Cat. No. CS-0614190
  • Purity ≥98%
  • MDL No. MFCD19228817
  • Storage RT, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₀O₂
  • Molecular Weight 114.14
  • Synonym(s) (1r,2R,3S)-2,3-Dimethylcyclopropane-1-carboxylic acid
  • SMILES O=C([C@H]1[C@@H]([C@@H]1C)C)O

Description

This chiral cyclopropane carboxylic acid features a rigid three-membered ring with defined stereochemistry at the 1,2,3-positions. The dimethyl substitution enhances structural stability and influences conformational rigidity, making it valuable for asymmetric synthesis and as a scaffold in medicinal chemistry.

Application

(1R,2R,3S)-2,3-Dimethylcyclopropane-1-carboxylic acid serves as a rigid, stereochemically defined building block for medicinal chemistry and natural product synthesis. Its cyclopropane core imparts conformational constraint, enabling precise spatial control in bioactive molecule design. The carboxylic acid functionality facilitates direct derivatization via esterification, amidation, or coupling reactions. Bench-stable and amenable to purification by standard chromatographic methods, it functions reliably in multi-step syntheses requiring stereoselective construction of quaternary centers.

Safety Information

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GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅱ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   0.973
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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