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CS-W001157 4
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4-Nitrophenyl-N-acetyl-β-D-glucosaminide

  • CAS No. 3459-18-5

  • Cat. No. CS-W011899
  • Purity≥97%
  • MDL No.MFCD00063696

*For research and further manufacturing use only, not for direct human use.

4-Nitrophenyl-N-acetyl-β-D-glucosaminide|CS-W011899

Structure of 3459-18-5

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General Information

  • CAS No. 3459-18-5
  • Cat. No. CS-W011899
  • Purity ≥97%
  • MDL No. MFCD00063696
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₈N₂O₈
  • Molecular Weight None
  • Synonym(s) None
  • SMILES CC(N[C@H]([C@H]([C@@H]([C@H](O1)CO)O)O)[C@@H]1OC2=CC=C(C=C2)[N+]([O-])=O)=O

Description

Hydrolyzed by N-acetyl-β-glucosaminidase in human urine, 4-Nitrophenyl N-acetyl-β-D-glucosaminide (CAS 3459-18-5) releases a yellow chromophore enabling real-time spectrophotometric quantification of enzymatic activity.

Application

4-Nitrophenyl N-acetyl-β-D-glucosaminide (CAS 3459-18-5) drives precise N-acetyl-β-D-glucosaminidase activity assays by releasing detectable 4-nitrophenol upon enzymatic cleavage. It also enables real-time chitinase ChiB1 profiling. Researchers use this substrate to monitor degranulation in rat basophilic leukemia RBL-2H3 cells, revealing key immune response dynamics.

Synthesis

  • Route1
    • p-Nitrophenyl 2-acetamido-3,4,6-tri-O-acetyl-β-D-glucopyranoside|CS-0347632
      13089-27-5
    • ~99%
    • In-stock
      4-Nitrophenyl-N-acetyl-β-D-glucosaminide|CS-W011899
      3459-18-5

    References

    • Roy, Rene; Tropper, Francois D.; Morrison, Tara; Boratynski, Janusz Journal of the Chemical Society, Chemical Communications, 1991 , # 7 p. 536 - 538
  • Route2

    References

    • Carbohydrate Research, , vol. 279, p. 293 - 306
  • Route3
    • null|null
      100-02-7
    • ~%
    • In-stock
      4-Nitrophenyl-N-acetyl-β-D-glucosaminide|CS-W011899
      3459-18-5

    References

    • Carbohydrate Research, , vol. 342, # 15 p. 2212 - 2222

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   151.39
  • LogP   -1.0827
  • H_Acceptors   8
  • H_Donors   4
  • Rotatable_Bonds   5

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