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CS-W001157 4
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Atorvastatin methyl ester

  • CAS No. 345891-62-5

  • Cat. No. CS-0112184
  • Molecule weight572.67
  • Purity≥98%
  • MDL No.MFCD21363420

*For research and further manufacturing use only, not for direct human use.

Atorvastatin methyl ester|CS-0112184

Structure of 345891-62-5

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General Information

  • CAS No. 345891-62-5
  • Cat. No. CS-0112184
  • Purity ≥98%
  • MDL No. MFCD21363420
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃₄H₃₇FN₂O₅
  • Molecular Weight 572.67
  • Synonym(s) None
  • SMILES O=C(C1=C(C(C)C)N(CC[C@@H](O)C[C@@H](O)CC(OC)=O)C(C2=CC=C(F)C=C2)=C1C3=CC=CC=C3)NC4=CC=CC=C4

Synthesis

  • Route1
    • methyl 2-((4R,6R)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4- (phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4- yl)acetate|CS-0914014
      1353049-81-6
    • ~94%
    • In-stock
      Atorvastatin methyl ester|CS-0112184
      345891-62-5

    References

    • Chen, Xiaofei; Xiong, Fangjun; Chen, Wenxue; He, Qiuqin; Chen, Fener Journal of Organic Chemistry, 2014 , vol. 79, # 6 p. 2723 - 2728
  • Route2

    References

    • British Journal of Pharmacology, , vol. 132, # 6 p. 1183 - 1192
  • Route3
    • null|null
      67-56-1
    • In-stock
      Atorvastatin|CS-2798
      134523-00-5
    • ~%
    • In-stock
      Atorvastatin methyl ester|CS-0112184
      345891-62-5

    References

    • Stach, Jan; Havlicek, Jaroslav; Placek, Lukas; Radl, Stanislav Collection of Czechoslovak Chemical Communications, 2008 , vol. 73, # 2 p. 229 - 246

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS08
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H361
Precautionary Statements : P280-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   100.79
  • LogP   6.402
  • H_Acceptors   6
  • H_Donors   3
  • Rotatable_Bonds   12

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