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CS-W001157 4
Total: USD 88.00

(S)-1-tert-Butyl 4-methyl 2-aminosuccinate hydrochloride

  • CAS No. 34582-30-4

  • Cat. No. CS-W006467
  • Purity≥96%
  • MDL No.MFCD05662354

*For research and further manufacturing use only, not for direct human use.

(S)-1-tert-Butyl 4-methyl 2-aminosuccinate hydrochloride|CS-W006467

Structure of 34582-30-4

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General Information

  • CAS No. 34582-30-4
  • Cat. No. CS-W006467
  • Purity ≥96%
  • MDL No. MFCD05662354
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₈ClNO₄
  • Molecular Weight 239.70
  • Synonym(s) L-Aspartic acid α-t-butyl, β-methyl ester hydrochloride
  • SMILES O=C(OC(C)(C)C)[C@@H](N)CC(OC)=O.[H]Cl

Description

(S)-1-tert-Butyl 4-methyl 2-aminosuccinate hydrochloride features a chiral succinate core with a tert-butyl ester and methyl substituent, delivering a bench-stable, moisture-tolerant scaffold for asymmetric synthesis. The protonated amine enhances solubility in polar solvents, enabling efficient coupling reactions in peptide analog development and catalyst design.

Application

(S)-1-tert-Butyl 4-methyl 2-aminosuccinate hydrochloride serves as a chiral building block for the synthesis of bioactive molecules, enabling efficient access to pyrrolidine and piperidine derivatives via reductive amination or cyclization. The protected amine and ester functionalities offer excellent functional group tolerance, facilitating downstream transformations in medicinal chemistry campaigns. Its bench-stable solid form simplifies handling and purification in multi-step syntheses.

Synthesis

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      (S)-1-tert-Butyl 4-methyl 2-aminosuccinate hydrochloride|CS-W006467
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    References

    • Baldwin; North; Flinn Tetrahedron, 1988 , vol. 44, # 2 p. 637 - 642

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   78.62
  • LogP   0.6403
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   3

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