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CS-W001157 4
Total: USD 88.00

2-(Dimethylamino)-4,6-dimethylpyrimidin-5-ol

  • CAS No. 345642-90-2

  • Cat. No. CS-0499933
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-(Dimethylamino)-4,6-dimethylpyrimidin-5-ol|CS-0499933

Structure of 345642-90-2

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General Information

  • CAS No. 345642-90-2
  • Cat. No. CS-0499933
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₃N₃O
  • Molecular Weight 167.21
  • Synonym(s) pyrimidinol
  • SMILES CN(C)C1=NC(C)=C(O)C(C)=N1

Synthesis

  • Route1
    • null|null
      1083329-39-8
    • ~99%
    • 2-(Dimethylamino)-4,6-dimethylpyrimidin-5-ol|CS-0499933
      345642-90-2

    References

    • ARIZONA BOARD OF REGENTS; HECHT, Sidney; ARMSTRONG, Jeffrey; KHDOUR, Omar; LU, Jun; ARCE, Pablo Patent: WO2011/103536 A1, 2011 ; Location in patent: Page/Page column 41-42 ; WO 2011/103536 A1
  • Route2
    • 5-Bromo-N,N,4,6-tetramethylpyridin-2-amine|CS-0754488
      627098-10-6
    • ~35%
    • 2-(Dimethylamino)-4,6-dimethylpyrimidin-5-ol|CS-0499933
      345642-90-2

    References

    • ARIZONA BOARD OF REGENTS; HECHT, Sidney; ARMSTRONG, Jeffrey; KHDOUR, Omar; LU, Jun; ARCE, Pablo Patent: WO2011/103536 A1, 2011 ; Location in patent: Page/Page column 48-49 ; WO 2011/103536 A1
  • Route3
    • 1,1-Dimethylguanidine (sulfate)-1|CS-1356870
      311-77-3
    • Pyruvic aldehyde 40%w/w in water|CS-0031856
      78-98-8
    • ~27%
    • 2-(Dimethylamino)-4,6-dimethylpyrimidin-5-ol|CS-0499933
      345642-90-2

    References

    • Renard, Brice-Loic; Boucherle, Benjamin; Maurin, Bruno; Molina, Marie-Carmen; Norez, Caroline; Becq, Frederic; Decout, Jean-Luc European Journal of Medicinal Chemistry, 2011 , vol. 46, # 5 p. 1935 - 1941

Safety Information

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GHS Pictogram : N/A
GHS No : N/A
Signal Word : N/A
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

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Computational Chemistry Data

  • TPSA   49.25
  • LogP   0.86504
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   1

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