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CS-W001157 4
Total: USD 88.00

2,3-Dioxoindoline-5-sulfonamide

  • CAS No. 3456-82-4

  • Cat. No. CS-0431746
  • Molecule weight226.21
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2,3-Dioxoindoline-5-sulfonamide|CS-0431746

Structure of 3456-82-4

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General Information

  • CAS No. 3456-82-4
  • Cat. No. CS-0431746
  • Purity ≥95%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₆N₂O₄S
  • Molecular Weight 226.21
  • Synonym(s) 2,3-dioxo-2,3-dihydro-1H-indole-5-sulfonamide
  • SMILES O=S(C1=CC2=C(NC(C2=O)=O)C=C1)(N)=O

Synthesis

  • Route1
    • 2,3-Dioxoindoline-5-sulfonyl chloride|CS-0054756
      132898-96-5
    • ~47%
    • 2,3-Dioxoindoline-5-sulfonamide|CS-0431746
      3456-82-4

    References

    • Lawrence, Harshani R.; Pireddu, Roberta; Chen, Liwei; Luo, Yunting; Sung, Shen-Shu; Szymanski, Ann Marie; Yip, M. L. Richard; Guida, Wayne C.; Sebti, Said M.; Wu, Jie; Lawrence, Nicholas J. Journal of Medicinal Chemistry, 2008 , vol. 51, # 16 p. 4948 - 4956
  • Route2

    References

    • NeuroSearch A/S Patent: US5198461 A1, 1993 ;
  • Route3
    • null|null
      302-17-0
    • Sulfanilamide Sulfadimethoxine  Impurity|CS-0229022
      63-74-1
    • ~%
    • 2,3-Dioxoindoline-5-sulfonamide|CS-0431746
      3456-82-4

    References

    • Vintonyak, Viktor V.; Warburg, Karin; Over, Bjoern; Huebel, Katja; Rauh, Daniel; Waldmann, Herbert Tetrahedron, 2011 , vol. 67, # 35 p. 6713 - 6729

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   106.33
  • LogP   -0.5312
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   1

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