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CS-W001157 4
Total: USD 88.00

6-Methoxy-2-naphthaldehyde

  • CAS No. 3453-33-6

  • Cat. No. CS-W016900
  • Purity≥98%
  • MDL No.MFCD00081152

*For research and further manufacturing use only, not for direct human use.

6-Methoxy-2-naphthaldehyde|CS-W016900

Structure of 3453-33-6

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General Information

  • CAS No. 3453-33-6
  • Cat. No. CS-W016900
  • Purity ≥98%
  • MDL No. MFCD00081152
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₀O₂
  • Molecular Weight 186.21
  • Synonym(s) LABOTEST-BB LT01147524; 6-Methoxy-2-naphthaldehyde
  • SMILES C1=C(C=O)C=CC2=C1C=CC(=C2)OC

Description

6-Methoxy-2-naphthaldehyde can be prepared by reacting 2-bromo 6-methoxy naphthalene with triethylorthoformate via Grignard reaction. Its crystals belong to the orthorhombic space group, P212121 and shows excellent NLO (non-linear optical) property.6-Methoxy-2-naphthaldehyde may be used in the preparation of the following 4-(6-methoxy-2-naphthyl)butan-2-one related compounds:4-(6-methoxy-2-naphthyl)but-3-en-2-one4-(6-methoxy-2-naphthyl)-3-methylbutan-2-one5-(6-methoxy-2-naphthyl)pentan-3-oneIt may also be used in the synthesis of the following chalcone derivatives:(2E)-1-(2-hydroxyphenyl)-3-(6-methoxy-2-naphthyl)prop-2-en-1-one(2E)-1-(2-chloropyridin-4-yl)-3-(6-methoxy-2-naphthyl)prop-2-en-1-one(2E)-3-(6-methoxy-2-naphthyl)-1-pyridin-4-ylprop-2-en-1-one(2E)-1-(2,4-dichlorophenyl)-3-(6-methoxy-2-naphthyl)prop-2-en-1-one

Synthesis

  • Route1
    • 2-Bromo-6-methoxynaphthalene|CS-0229672
      5111-65-9
    • null|null
      68-12-2
    • ~95%
    • In-stock
      6-Methoxy-2-naphthaldehyde|CS-W016900
      3453-33-6

    References

    • Bioorganic and Medicinal Chemistry, , vol. 12, # 16 p. 4313 - 4336
  • Route2
    • null|null
      201230-82-2
    • 2-Bromo-6-methoxynaphthalene|CS-0229672
      5111-65-9
    • ~94%
    • In-stock
      6-Methoxy-2-naphthaldehyde|CS-W016900
      3453-33-6

    References

    • Chemistry - An Asian Journal, , vol. 7, # 10 p. 2213 - 2216
  • Route3
    • Naproxen impurity 6|CS-0259671
      67886-70-8
    • ~22%
    • In-stock
      6-Methoxy-2-naphthaldehyde|CS-W016900
      3453-33-6

    References

    • Journal of the American Chemical Society, , vol. 116, # 22 p. 9869 - 9882

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

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Computational Chemistry Data

  • TPSA   26.3
  • LogP   2.6609
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   2

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