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CS-W001157 4
Total: USD 88.00

Diethyl (2-oxo-2-phenylethyl)phosphonate

  • CAS No. 3453-00-7

  • Cat. No. CS-0037093
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Diethyl (2-oxo-2-phenylethyl)phosphonate|CS-0037093

Structure of 3453-00-7

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General Information

  • CAS No. 3453-00-7
  • Cat. No. CS-0037093
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₇O₄P
  • Molecular Weight 256.23
  • Synonym(s) Diethyl(2-oxo-2-phenylethyl)phosphonate
  • SMILES O=P(OCC)(CC(C1=CC=CC=C1)=O)OCC

Description

Reactant involved in:Asymmetric Michael addition of -oxo phosphonates to nitro olefinsGem-chlorofluorination of keto phosphonates with subsequent functionalization of the productsCyclocondensation reactions to produce arylphosphonatesDiazo transfer reactions for synthesis of diazo-phosphonyl compoundsHorner-Wadsworth-Emmons reactionsInverse-electron-demand Diels-Alder reactions

Synthesis

  • Route1
    • null|null
      3450-67-7
    • ~95%
    • In-stock
      Diethyl (2-oxo-2-phenylethyl)phosphonate|CS-0037093
      3453-00-7

    References

    • Li, Xiubin; Hu, Gaobo; Luo, Ping; Tang, Guo; Gao, Yuxing; Xu, Pengxiang; Zhao, Yufen Advanced Synthesis and Catalysis, 2012 , vol. 354, # 13 p. 2427 - 2432
  • Route2
    • null|null
      683-08-9
    • null|null
      98-88-4
    • ~88%
    • In-stock
      Diethyl (2-oxo-2-phenylethyl)phosphonate|CS-0037093
      3453-00-7

    References

    • Nesterov; Kolodiazhnyi Tetrahedron, 2007 , vol. 63, # 29 p. 6720 - 6731
  • Route3
    • In-stock
      2-(Diethoxyphosphoryl)acetic acid|CS-W007893
      3095-95-2
    • null|null
      98-88-4
    • ~80%
    • In-stock
      Diethyl (2-oxo-2-phenylethyl)phosphonate|CS-0037093
      3453-00-7

    References

    • Corbel, Bernard; L'Hostis-Kervella, Isabelle; Haelters, Jean-Pierre Synthetic Communications, 2000 , vol. 30, # 4 p. 609 - 618

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   52.6
  • LogP   3.1354
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   7

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