Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

5-Bromo-3-phenylpyrazin-2-amine

  • CAS No. 344940-70-1

  • Cat. No. CS-0122297
  • Molecule weight250.09
  • Purity≥97%
  • MDL No.MFCD12547094

*For research and further manufacturing use only, not for direct human use.

5-Bromo-3-phenylpyrazin-2-amine|CS-0122297

Structure of 344940-70-1

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 344940-70-1
  • Cat. No. CS-0122297
  • Purity ≥97%
  • MDL No. MFCD12547094
  • Storage 4°C, sealed storage, away from moisture and light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₈BrN₃
  • Molecular Weight 250.09
  • Synonym(s) 2-Amino-5-bromo-3-phenylpyrazine
  • SMILES NC1=NC=C(Br)N=C1C2=CC=CC=C2

Description

5-Bromo-3-phenylpyrazin-2-amine features a brominated pyrazine core paired with a phenyl substituent, delivering enhanced electronic modulation and structural rigidity. This scaffold integrates readily into transition-metal-catalyzed coupling reactions, enabling efficient access to complex heteroaromatic architectures in medicinal chemistry and materials science applications.

Application

5-Bromo-3-phenylpyrazin-2-amine serves as a versatile building block in the synthesis of functionalized pyrazine-based scaffolds. Its bromo group enables palladium-catalyzed cross-coupling reactions, while the pyrazin-2-amine functionality offers sites for further derivatization via amidation or metal-mediated transformations. The compound exhibits good bench stability and facilitates efficient access to heterocyclic frameworks relevant to medicinal chemistry and materials science.

Synthesis

  • Route1

    References

    • BRISTOL-MYERS SQUIBB COMPANY Patent: WO2009/155389 A1, 2009 ; Location in patent: Page/Page column 85-86 ; WO 2009/155389 A1
  • Route2

    References

    • Adamczyk, Maciej; Akireddy, Srinivasa Rao; Johnson, Donald D.; Mattingly, Phillip G.; Pan, You; Reddy, Rajarathnam E. Tetrahedron, 2003 , vol. 59, # 41 p. 8129 - 8142
  • Route3

    References

    • Wu, Chun; Nakamura, Hideshi; Murai, Akio; Shimomura, Osamu Tetrahedron Letters, 2001 , vol. 42, # 16 p. 2997 - 3000

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   51.8
  • LogP   2.4883
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 5-Bromo-3-phenylpyrazin-2-amine sigma5-Bromo-3-phenylpyrazin-2-amine manufacturer5-Bromo-3-phenylpyrazin-2-amine price5-Bromo-3-phenylpyrazin-2-amine structure5-Bromo-3-phenylpyrazin-2-amine SDSbuy 5-Bromo-3-phenylpyrazin-2-amine5-Bromo-3-phenylpyrazin-2-amine supplier5-Bromo-3-phenylpyrazin-2-amine uses5-Bromo-3-phenylpyrazin-2-amine molecular weightprice of 5-Bromo-3-phenylpyrazin-2-amine5-Bromo-3-phenylpyrazin-2-amine chemical name formula of 5-Bromo-3-phenylpyrazin-2-amine
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label