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Structure of 34486-22-1
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2-Chloro-6-(trifluoromethyl)pyridin-4-amine features a trifluoromethyl group that enhances electron deficiency and metabolic stability, while the chloro substituent enables selective coupling reactions. This pyridine scaffold integrates readily into pharmaceutical intermediates and agrochemicals, offering high reactivity under standard conditions with excellent bench stability.
2-Chloro-6-(trifluoromethyl)pyridin-4-amine serves as a versatile building block in medicinal chemistry, enabling efficient construction of heterocyclic scaffolds via palladium-catalyzed cross-coupling reactions. Its trifluoromethyl group enhances metabolic stability and lipophilicity, while the chloro and amine functionalities offer orthogonal reactivity for further functionalization. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for high-throughput synthesis and API development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: