(S)-N-Methylpyrrolidine-2-methanol

Name: (S)-N-Methylpyrrolidine-2-methanol
Brand: ChemScene
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CAS No. 34381-71-0
Cat. No. CS-0030792
Purity≥97%
MDL No.MFCD00011727

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
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(S)-N-Methylpyrrolidine-2-methanol|CS-0030792

Structure of 34381-71-0

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Description

Precursor to phosphine ligands for catalytic asymmetric Grignard cross-coupling reactions.

Application

(S)-N-Methylpyrrolidine-2-methanol serves as a versatile chiral building block in medicinal chemistry, enabling efficient access to bioactive heterocycles. Its pendant hydroxyl group facilitates derivatization via esterification, etherification, or oxidation, while the tertiary amine supports salt formation and solubility enhancement. The molecule exhibits excellent bench stability and functional group tolerance, making it well-suited for modular synthesis workflows and scale-up applications.

General Information

CAS No. 34381-71-0
Cat. No. CS-0030792
Purity ≥97%
MDL No. MFCD00011727
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₁₃NO
Molecular Weight 115.17
Synonym(s) P-Tolylsulfonylmethylnitrosamide diazald
SMILES OC[C@H]1N(CCC1)C

Computational Chemistry Data

TPSA 23.47
LogP 0.0729
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H227-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Bioactive Molecules Dye and Bio-assay Reagents

Building Blocks Functional Group Alcohol

Building Blocks Skeleton Aliphatic heterocycle compounds Pyrrolidine compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Life Science Amino Acids and their Derivatives Proline and derivatives

Chemical Biology Peptide Chemistry Unnatural Amino Acid Derivatives

Drug Discovery Cancer KRAS

Key Words

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(S)-N-Methylpyrrolidine-2-methanol

CAS No. 34381-71-0

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