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CS-W001157 4
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(R)-2-Acetamidobutanoic acid

  • CAS No. 34271-27-7

  • Cat. No. CS-0153928
  • Purity≥96%
  • MDL No.MFCD01862370

*For research and further manufacturing use only, not for direct human use.

(R)-2-Acetamidobutanoic acid|CS-0153928

Structure of 34271-27-7

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General Information

  • CAS No. 34271-27-7
  • Cat. No. CS-0153928
  • Purity ≥96%
  • MDL No. MFCD01862370
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₁NO₃
  • Molecular Weight 145.16
  • Synonym(s) Acetyl-D-2-aminobutyric acid
  • SMILES CC[C@@H](NC(C)=O)C(O)=O

Description

(R)-2-Acetamidobutanoic acid is a chiral building block featuring a defined stereochemistry at the C2 position, enabling precise incorporation into peptide mimetics and bioactive molecule scaffolds. The acetamido group provides a polar, hydrogen-bonding handle, while the carboxylic acid offers versatility in derivatization. This compound exhibits bench-stable handling characteristics and compatibility with standard synthetic protocols in medicinal chemistry workflows.

Application

(R)-2-Acetamidobutanoic acid serves as a valuable chiral building block for the synthesis of bioactive molecules, particularly in peptide-based drug discovery. Its well-defined stereochemistry and stability under standard reaction conditions enable reliable incorporation into complex scaffolds. The molecule functions effectively in amide bond formation and facilitates derivatization via its carboxylic acid and acetamide groups, offering versatile access to functionalized intermediates used in medicinal chemistry and process development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   66.4
  • LogP   -0.0143
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   3

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