Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

4-Chloro-3-hydroxybenzoic acid

  • CAS No. 34113-69-4

  • Cat. No. CS-W005466
  • Purity≥98%
  • MDL No.MFCD00153892

*For research and further manufacturing use only, not for direct human use.

4-Chloro-3-hydroxybenzoic acid|CS-W005466

Structure of 34113-69-4

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 34113-69-4
  • Cat. No. CS-W005466
  • Purity ≥98%
  • MDL No. MFCD00153892
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅ClO₃
  • Molecular Weight 172.57
  • Synonym(s) 5-Carboxy-2-chlorophenol
  • SMILES C1=C(C(=CC=C1C(O)=O)Cl)O

Description

4-Chloro-3-hydroxybenzoic acid features a hydroxyl group ortho to the carboxylic acid and a chlorine substituent at the para position, enabling diverse functionalization. This electron-deficient aromatic scaffold integrates readily into bioactive molecule frameworks, offering enhanced solubility and stability under standard conditions.

Application

4-Chloro-3-hydroxybenzoic acid serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the phenolic hydroxyl and carboxylic acid sites. Its ortho-chloro substituent enhances electrophilic substitution reactivity and provides a handle for palladium-catalyzed coupling reactions. The compound exhibits bench stability and facilitates straightforward derivatization, including esterification, amide formation, and Suzuki-Miyaura cross-coupling, making it well-suited for the synthesis of complex heterocyclic scaffolds and API intermediates.

Synthesis

  • Route1
    • null|null
      931409-94-8
    • ~92%
    • In-stock
      4-Chloro-3-hydroxybenzoic acid|CS-W005466
      34113-69-4

    References

    • PFIZER LIMITED Patent: WO2007/34325 A1, 2007 ; Location in patent: Page/Page column 53 ; WO 2007/034325 A1
  • Route2

    References

    • DE74493 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 3, p. 847
  • Route3

    References

    • Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), , # 6 p. 985 - 988

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07,GHS09
Signal Word : Warning
UN#: 3077
Class : 9
Packing Group : Ⅲ
Hazard Statements : H302-H315-H319-H335-H400
Precautionary Statements : P261-P264-P270-P271-P273-P280-P302+P352-P304+P340-P330-P362+P364-P391-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   57.53
  • LogP   1.7438
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 4-Chloro-3-hydroxybenzoic acid sigma4-Chloro-3-hydroxybenzoic acid manufacturer4-Chloro-3-hydroxybenzoic acid price4-Chloro-3-hydroxybenzoic acid structure4-Chloro-3-hydroxybenzoic acid SDSbuy 4-Chloro-3-hydroxybenzoic acid4-Chloro-3-hydroxybenzoic acid supplier4-Chloro-3-hydroxybenzoic acid uses4-Chloro-3-hydroxybenzoic acid molecular weightprice of 4-Chloro-3-hydroxybenzoic acid4-Chloro-3-hydroxybenzoic acid chemical name formula of 4-Chloro-3-hydroxybenzoic acid
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label