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CS-W001157 4
Total: USD 88.00

Methyl 2-(phenylsulfonyl)acetate

  • CAS No. 34097-60-4

  • Cat. No. CS-0133099
  • Molecule weight214.24
  • Purity≥98%
  • MDL No.MFCD00007555

*For research and further manufacturing use only, not for direct human use.

Methyl 2-(phenylsulfonyl)acetate|CS-0133099

Structure of 34097-60-4

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General Information

  • CAS No. 34097-60-4
  • Cat. No. CS-0133099
  • Purity ≥98%
  • MDL No. MFCD00007555
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₀O₄S
  • Molecular Weight 214.24
  • Synonym(s) Phenylsulfonylacetic Acid Methyl Ester
  • SMILES O=C(OC)CS(=O)(C1=CC=CC=C1)=O

Description

Methyl phenylsulfonylacetate has been used:in a key step during the synthesis of ()-hybridalactone, marine eicosanoid isolated from the red alga Laurencia hybridain dehydrative alkylation of alcohols under modified Mitsunobu conditions followed by desulfonylation using magnesiumin three step synthesis of 2-(hydroxymethyl)indene

Application

Methyl 2-(phenylsulfonyl)acetate serves as a versatile synthon in organic synthesis, enabling efficient construction of sulfonamide and sulfonic acid derivatives. Its stability under standard reaction conditions and compatibility with nucleophilic substitution, reduction, and cross-coupling protocols facilitate the modular assembly of bioactive scaffolds. The phenylsulfonyl group enhances regioselectivity in functionalization reactions and aids purification through crystallization or chromatographic separation.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   60.44
  • LogP   0.6333
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   3

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