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CS-W001157 4
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2,3-Dihydroxy-N,N,N-trimethylpropan-1-aminium chloride

  • CAS No. 34004-36-9

  • Cat. No. CS-0163235
  • Molecule weight169.65
  • Purity≥97%
  • MDL No.MFCD01668726

*For research and further manufacturing use only, not for direct human use.

2,3-Dihydroxy-N,N,N-trimethylpropan-1-aminium chloride|CS-0163235

Structure of 34004-36-9

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General Information

  • CAS No. 34004-36-9
  • Cat. No. CS-0163235
  • Purity ≥97%
  • MDL No. MFCD01668726
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₆ClNO₂
  • Molecular Weight 169.65
  • Synonym(s) (2,3-Dihydroxypropyl)trimethylammonium chloride
  • SMILES C[N+](C)(C)CC(O)CO.[Cl-]

Description

This quaternary ammonium salt features a dihydroxypropan-1-amine core with trimethylammonium functionality, delivering high solubility in aqueous systems. The chloride counterion ensures stability under standard conditions. Designed for use in synthetic transformations requiring polar, charged intermediates, it serves as a robust platform for bioconjugation and phase-transfer catalysis applications.

Application

2,3-Dihydroxy-N,N,N-trimethylpropan-1-aminium chloride serves as a stable, water-soluble chiral building block for the synthesis of complex polyols and glycosylation intermediates. Its dual hydroxyl groups enable selective protection and derivatization, while the quaternary ammonium functionality provides solubility and facilitates ion-exchange purification. This compound functions effectively in carbohydrate chemistry workflows and supports the construction of biologically relevant scaffolds under mild reaction conditions.

Synthesis

  • Route1
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      96-24-2
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      75-50-3
    • ~%
    • In-stock
      2,3-Dihydroxy-N,N,N-trimethylpropan-1-aminium chloride|CS-0163235
      34004-36-9

    References

    • Hanriot Annales de Chimie (Cachan, France), 1879 , vol. <5> 17, p. 114
  • Route2

    References

    • Klein, Emmanuel; Ciobanu, Miahala; Klein, Jerome; MacHi, Valerie; Leborgne, Christian; Vandamme, Thierry; Frisch, Benoit; Pons, Francoise; Kichler, Antoine; Zuber, Guy; Lebeau, Luc Bioconjugate Chemistry, 2010 , vol. 21, # 2 p. 360 - 371

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   -3.9502
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   3

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