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CS-W001157 4
Total: USD 88.00

1-Methyl-2-oxo-1,2-dihydropyridine-4-carboxylic acid

  • CAS No. 33972-97-3

  • Cat. No. CS-W018078
  • Purity≥96%
  • MDL No.MFCD03701415

*For research and further manufacturing use only, not for direct human use.

1-Methyl-2-oxo-1,2-dihydropyridine-4-carboxylic acid|CS-W018078

Structure of 33972-97-3

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General Information

  • CAS No. 33972-97-3
  • Cat. No. CS-W018078
  • Purity ≥96%
  • MDL No. MFCD03701415
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₇NO₃
  • Molecular Weight 153.14
  • Synonym(s) 1-Methylthyl-2-oxo-1,2-dihydropyridine-4-carboxylic acid
  • SMILES O=C(C(C=CN1C)=CC1=O)O

Description

1-Methyl-2-oxo-1,2-dihydropyridine-4-carboxylic acid features a conjugated dihydropyridone core with a methyl group at the 1-position and a carboxylic acid at the 4-position. This electron-deficient heterocycle serves as a key building block in synthetic routes to bioactive compounds, offering enhanced stability and reactivity in cross-coupling and cyclization processes under standard conditions.

Application

1-Methyl-2-oxo-1,2-dihydropyridine-4-carboxylic acid serves as a versatile building block in heterocyclic synthesis, enabling efficient access to pyridine-based scaffolds. Its carboxylic acid functionality facilitates direct derivatization, while the enone system supports Michael additions and cycloadditions. Bench-stable and amenable to standard purification methods, it functions effectively in multi-step synthetic sequences requiring functional group compatibility and predictable reactivity.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   59.3
  • LogP   0.0835
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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