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CS-W001157 4
Total: USD 88.00

4-Methoxy-2-nitrobenzoic acid

  • CAS No. 33844-21-2

  • Cat. No. CS-W001541
  • Purity≥96%
  • MDL No.MFCD04972109
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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*For research and further manufacturing use only, not for direct human use.

4-Methoxy-2-nitrobenzoic acid|CS-W001541

Structure of 33844-21-2

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Description

4-Methoxy-2-nitrobenzoic acid features a para-methoxy group and an ortho-nitro substituent on the benzoic acid scaffold, creating a highly electron-deficient aromatic core. This structural arrangement enhances reactivity in coupling reactions and facilitates efficient derivatization under mild conditions. The molecule exhibits excellent stability and solubility in common organic solvents, enabling straightforward integration into synthetic workflows for pharmaceutical intermediates and functional materials.

Application

4-Methoxy-2-nitrobenzoic acid serves as a versatile building block in medicinal chemistry and materials science, enabling efficient access to functionalized aromatic systems. Its ortho-nitro and para-methoxy substituents provide complementary reactivity for selective transformations, including reduction of the nitro group to an amine or coupling via the carboxylic acid. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for use in multistep syntheses of heterocyclic scaffolds and API intermediates.

General Information

  • CAS No. 33844-21-2
  • Cat. No. CS-W001541
  • Purity ≥96%
  • MDL No. MFCD04972109
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₇NO₅
  • Molecular Weight 197.14
  • Synonym(s) benzoic acid, 4-methoxy-2-nitro-
  • SMILES O=C(O)C1=CC=C(OC)C=C1[N+]([O-])=O

Computational Chemistry Data

  • TPSA   89.67
  • LogP   1.3016
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   3

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302+H312+H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501

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