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Structure of 33844-21-2
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4-Methoxy-2-nitrobenzoic acid features a para-methoxy group and an ortho-nitro substituent on the benzoic acid scaffold, creating a highly electron-deficient aromatic core. This structural arrangement enhances reactivity in coupling reactions and facilitates efficient derivatization under mild conditions. The molecule exhibits excellent stability and solubility in common organic solvents, enabling straightforward integration into synthetic workflows for pharmaceutical intermediates and functional materials.
4-Methoxy-2-nitrobenzoic acid serves as a versatile building block in medicinal chemistry and materials science, enabling efficient access to functionalized aromatic systems. Its ortho-nitro and para-methoxy substituents provide complementary reactivity for selective transformations, including reduction of the nitro group to an amine or coupling via the carboxylic acid. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for use in multistep syntheses of heterocyclic scaffolds and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302+H312+H332
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501
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Lot numbers can be found on the outside label of a product: