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CS-W001157 4
Total: USD 88.00

(2-Iodophenyl)(methyl)sulfane

  • CAS No. 33775-94-9

  • Cat. No. CS-0142865
  • Purity≥98%
  • MDL No.MFCD00051611

*For research and further manufacturing use only, not for direct human use.

(2-Iodophenyl)(methyl)sulfane|CS-0142865

Structure of 33775-94-9

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General Information

  • CAS No. 33775-94-9
  • Cat. No. CS-0142865
  • Purity ≥98%
  • MDL No. MFCD00051611
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₇IS
  • Molecular Weight 250.10
  • Synonym(s) 2-Iodothioanisole
  • SMILES CSC1=CC=CC=C1I

Description

(2-Iodophenyl)(methyl)sulfane features a methylthio group attached to an ortho-iodinated phenyl ring, delivering a reactive handle for cross-coupling transformations. This bench-stable sulfane integrates readily into synthetic sequences requiring iodide-directed functionalization, enabling efficient access to complex aryl-thioether architectures under standard conditions.

Application

(2-Iodophenyl)(methyl)sulfane serves as a versatile building block in transition-metal-catalyzed cross-coupling reactions, enabling efficient construction of biaryl scaffolds. The iodide group facilitates reliable Pd- or Ni-mediated coupling, while the methylthio functionality offers stability and compatibility with standard synthetic workflows. Its bench-stable nature and predictable reactivity make it well-suited for medicinal chemistry and process development applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   0
  • LogP   3.0131
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

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