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CS-W001157 4
Total: USD 88.00

(Methoxymethyl)triphenylphosphonium bromide

  • CAS No. 33670-32-5

  • Cat. No. CS-W006206
  • Purity≥96%
  • MDL No.MFCD00075442

*For research and further manufacturing use only, not for direct human use.

(Methoxymethyl)triphenylphosphonium bromide|CS-W006206

Structure of 33670-32-5

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General Information

  • CAS No. 33670-32-5
  • Cat. No. CS-W006206
  • Purity ≥96%
  • MDL No. MFCD00075442
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₀H₂₀BrOP
  • Molecular Weight 387.25
  • Synonym(s) (methoxymethyl)triphenylphosphanium bromide
  • SMILES COC[P+](C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3.[Br-]

Description

(Methoxymethyl)triphenylphosphonium bromide delivers a stable, bench-ready phosphonium salt featuring a methoxymethyl group that enhances solubility and reactivity in polar media. This derivative enables efficient Wittig-type transformations with improved handling characteristics compared to traditional phosphonium salts.

Application

(Methoxymethyl)triphenylphosphonium bromide serves as a reliable reagent for the synthesis of α-alkylated carbonyl compounds via the Wittig-type reaction. It facilitates the formation of enol ether intermediates with high stereoselectivity and offers improved bench stability compared to traditional phosphonium salts. Its methoxymethyl group enables straightforward subsequent deprotection under mild acidic conditions, simplifying access to functionalized alkenes. The reagent exhibits excellent functional group tolerance and is well-suited for iterative synthetic sequences in complex molecule construction.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   9.23
  • LogP   0.5884
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   5

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