(R)-3-Aminopiperidine dihydrochloride

Name: (R)-3-Aminopiperidine dihydrochloride
Brand: ChemScene
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CAS No. 334618-23-4
Cat. No. CS-B0670
Purity≥95%
MDL No.MFCD06799458

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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(R)-3-Aminopiperidine dihydrochloride|CS-B0670

Structure of 334618-23-4

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General Information

CAS No. 334618-23-4
Cat. No. CS-B0670
Purity ≥95%
MDL No. MFCD06799458
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₁₄Cl₂N₂
Molecular Weight 173.08
Synonym(s) R-3-aminopiperidine dihydrochloride
SMILES N[C@H]1CNCCC1.Cl.Cl

Description

(R)-3-Aminopiperidine dihydrochloride is a bench-stable, moisture-tolerant chiral building block featuring a primary amine at the 3-position of a piperidine ring. This configuration enables direct incorporation into bioactive molecule synthesis, particularly in medicinal chemistry and peptide conjugation workflows. The dihydrochloride salt enhances solubility and handling in aqueous reaction systems.

Application

(R)-3-Aminopiperidine dihydrochloride serves as a key chiral building block in medicinal chemistry, enabling the synthesis of bioactive molecules through amine-functionalized heterocycles. Its well-defined stereochemistry and high reactivity facilitate efficient coupling reactions, peptide elongation, and incorporation into diverse scaffolds. The dihydrochloride salt enhances solubility and stability, simplifying handling and purification in standard synthetic workflows.

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

TPSA 38.05
LogP 0.5407
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 0

Other Classifications

Bioactive Molecules Natural Products

Building Blocks Functional Group Amine

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Building Blocks Skeleton Aliphatic heterocycle compounds Piperidine compounds

Key Words

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(R)-3-Aminopiperidine dihydrochloride

CAS No. 334618-23-4

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