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CS-W001157 4
Total: USD 88.00

Isopropoxy-acetic acid

  • CAS No. 33445-07-7

  • Cat. No. CS-0005425
  • Purity≥98%
  • MDL No.MFCD09055367

*For research and further manufacturing use only, not for direct human use.

Isopropoxy-acetic acid|CS-0005425

Structure of 33445-07-7

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General Information

  • CAS No. 33445-07-7
  • Cat. No. CS-0005425
  • Purity ≥98%
  • MDL No. MFCD09055367
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₀O₃
  • Molecular Weight 118.13
  • Synonym(s) Isopropoxyacetic acid
  • SMILES O=C(O)COC(C)C

Description

Isopropoxy-acetic acid features a polar ester group that enhances solubility in organic solvents while maintaining compatibility with aqueous systems. This functionalized acetic acid derivative integrates readily into synthetic pathways requiring controlled reactivity and moderate hydrophilicity, enabling efficient incorporation into complex molecular architectures under standard conditions.

Application

Isopropoxy-acetic acid serves as a versatile building block in synthetic organic chemistry, enabling efficient access to ester-functionalized intermediates. Its isopropyl ester group offers enhanced stability and ease of purification compared to more labile alkyl esters, while maintaining compatibility with standard hydrolysis, coupling, and reduction protocols. The molecule functions effectively in the synthesis of bioactive scaffolds and functional polymers, providing predictable reactivity under mild conditions.

Synthesis

  • Route1
    • null|null
      79-11-8
    • null|null
      67-63-0
    • ~64%
    • In-stock
      Isopropoxy-acetic acid|CS-0005425
      33445-07-7

    References

    • Denmark, Scott E.; Chung, Won-Jin Journal of Organic Chemistry, 2008 , vol. 73, # 12 p. 4582 - 4595
  • Route2
    • null|null
      1089707-47-0
    • ~%
    • In-stock
      Isopropoxy-acetic acid|CS-0005425
      33445-07-7

    References

    • WO2008/147544 A1, ; Page/Page column 111 ; WO 2008/147544 A1
  • Route3
    • null|null
      3926-62-3
    • null|null
      67-63-0
    • ~86%
    • In-stock
      Isopropoxy-acetic acid|CS-0005425
      33445-07-7

    References

    • VIFOR (INTERNATIONAL) AG Patent: US2012/202806 A1, 2012 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS08
Signal Word : Danger
UN#: 3265
Class : 8
Packing Group : Ⅱ
Hazard Statements : H302-H314-H361
Precautionary Statements : P260-P264-P270-P280-P301+P330+P331-P304+P340-P363-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   46.53
  • LogP   0.496
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   3

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