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CS-W001157 4
Total: USD 88.00

9,9-Dimethylfluorene-2-boronic acid

  • CAS No. 333432-28-3

  • Cat. No. CS-W003556
  • Purity≥96%
  • MDL No.MFCD08704227

*For research and further manufacturing use only, not for direct human use.

9,9-Dimethylfluorene-2-boronic acid|CS-W003556

Structure of 333432-28-3

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General Information

  • CAS No. 333432-28-3
  • Cat. No. CS-W003556
  • Purity ≥96%
  • MDL No. MFCD08704227
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₁₅BO₂
  • Molecular Weight 238.09
  • Synonym(s) 9,9'-Dimethylfluorene-2-Boronic Acid; 9,9-Dimethylfluorene-2-boronic acid
  • SMILES CC1(C2=CC=CC=C2C3=C1C=C(B(O)O)C=C3)C

Description

9,9-Dimethylfluorene-2-boronic acid features a sterically shielded boronic acid group attached to a rigid fluorene scaffold, enhancing stability and resistance to protodeboronation. This bench-stable reagent integrates readily into Suzuki-Miyaura coupling reactions, enabling efficient C–C bond formation under mild conditions with high functional group tolerance.

Application

9,9-Dimethylfluorene-2-boronic acid serves as a robust boronic acid building block for Suzuki-Miyaura cross-coupling reactions. Its sterically protected fluorene core enhances stability and minimizes protodeboronation, enabling reliable coupling with aryl, heteroaryl, and vinyl halides under standard conditions. The dimethyl substitution at the 9-position improves solubility and facilitates purification, making it well-suited for applications in medicinal chemistry and materials science.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313-P362+P364

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   1.6727
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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