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CS-W001157 4
Total: USD 88.00

4-Borono-1-naphthoic acid

  • CAS No. 332398-57-9

  • Cat. No. CS-0174735
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-Borono-1-naphthoic acid|CS-0174735

Structure of 332398-57-9

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General Information

  • CAS No. 332398-57-9
  • Cat. No. CS-0174735
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₉BO₄
  • Molecular Weight 216.00
  • Synonym(s) 4-Carboxynaphthalene-1-boronic acid
  • SMILES OB(O)C1=CC=C(C(O)=O)C2=CC=CC=C21

Description

4-Borono-1-naphthoic acid features a boronate group appended to the naphthalene scaffold, enabling selective conjugation in bioorthogonal chemistry. This electron-deficient aryl boronate integrates readily into synthetic workflows, offering enhanced stability under standard conditions and facilitating downstream functionalization through palladium-catalyzed coupling or transborylation reactions.

Application

4-Borono-1-naphthoic acid serves as a versatile building block in transition-metal-catalyzed cross-coupling reactions, enabling efficient construction of biaryl and heteroaryl scaffolds. Its boronic acid functionality exhibits excellent bench stability and compatibility with diverse functional groups, facilitating straightforward purification and integration into complex molecule synthesis. This compound functions effectively in Suzuki-Miyaura coupling protocols, offering reliable yields and predictable regiochemistry for the assembly of naphthalene-based pharmaceutical intermediates and advanced materials.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   77.76
  • LogP   0.2178
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   2

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