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CS-W001157 4
Total: USD 88.00

2-Chloro-4H-thieno[3,2-b]pyrrole-5-carboxylic acid

  • CAS No. 332099-40-8

  • Cat. No. CS-0309231
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-Chloro-4H-thieno[3,2-b]pyrrole-5-carboxylic acid|CS-0309231

Structure of 332099-40-8

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General Information

  • CAS No. 332099-40-8
  • Cat. No. CS-0309231
  • Purity ≥97%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₄ClNO₂S
  • Molecular Weight 201.63
  • Synonym(s) None
  • SMILES C1=C(C(=O)O)NC2=C1SC(=C2)Cl

Synthesis

  • Route1
    • Ethyl 2-chloro-4H-thieno[3,2-b]pyrrole-5-carboxylate|CS-0327778
      332099-38-4
    • ~%
    • 2-Chloro-4H-thieno[3,2-b]pyrrole-5-carboxylic acid|CS-0309231
      332099-40-8

    References

    • Parmentier, Jean-Gilles; Portevin, Bernard; Golsteyn, Roy M.; Pierre, Alain; Hickman, John; Gloanec, Philippe; De Nanteuil, Guillaume Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 3 p. 841 - 844
  • Route2

    References

    • Venable, Jennifer D.; Cai, Hui; Chai, Wenying; Dvorak, Curt A.; Grice, Cheryl A.; Jablonowski, Jill A.; Shah, Chandra R.; Kwok, Annette K.; Ly, Kiev S.; Pio, Barbara; Wei, Jianmei; Desai, Pragnya J.; Jiang, Wen; Nguyen, Steven; Ling, Ping; Wilson, Sandy J.; Dunford, Paul J.; Thurmond, Robin L.; Lovenberg, Timothy W.; Karlsson, Lars; Carruthers, Nicholas I.; Edwards, James P. Journal of Medicinal Chemistry, 2005 , vol. 48, # 26 p. 8289 - 8298
  • Route3
    • Methyl 2-chloro-4H-thieno[3,2-b]pyrrole-5-carboxylate|CS-0080388
      403860-08-2
    • ~%
    • 2-Chloro-4H-thieno[3,2-b]pyrrole-5-carboxylic acid|CS-0309231
      332099-40-8

    References

    • Whittamore, Paul R.O.; Addie, Matthew S.; Bennett, Stuart N.L.; Birch, Alan M.; Butters, Michael; Godfrey, Linda; Kenny, Peter W.; Morley, Andrew D.; Murray, Paul M.; Oikonomakos, Nikos G.; Otterbein, Ludovic R.; Pannifer, Andrew D.; Parker, Jeremy S.; Readman, Kristy; Siedlecki, Pawel S.; Schofield, Paul; Stocker, Andy; Taylor, Melvyn J.; Townsend, Linda A.; Whalley, David P.; Whitehouse, Jennifer Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 21 p. 5567 - 5571

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H317
Precautionary Statements : P261-P264-P270-P272-P280-P302+P352-P330-P362+P364-P501

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Computational Chemistry Data

  • TPSA   53.09
  • LogP   2.581
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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