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Structure of 331958-90-8
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This boronate ester features a tetrahydrofuran-3-yl substituent that enhances solubility and stability, enabling efficient cross-coupling under standard conditions. The sterically hindered tetramethyl groups confer exceptional bench stability, while the dioxaborolane core facilitates reliable Suzuki-Miyaura reactions with minimal decomposition.
4,4,5,5-Tetramethyl-2-(tetrahydrofuran-3-yl)-1,3,2-dioxaborolane serves as a stable, bench-ready boron reagent for Suzuki-Miyaura cross-coupling reactions. Its tetramethyl-substituted dioxaborolane core enhances air and moisture stability, while the tetrahydrofuran-3-yl group imparts improved solubility and compatibility with polar reaction media. This reagent enables efficient coupling with aryl, heteroaryl, and vinyl halides under mild conditions, facilitating rapid construction of biaryl and conjugated systems in medicinal chemistry and materials synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: