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CS-W001157 4
Total: USD 88.00

2-(Thiophen-2-yl)pyridine

  • CAS No. 3319-99-1

  • Cat. No. CS-W013265
  • Purity≥97%
  • MDL No.MFCD00044441

*For research and further manufacturing use only, not for direct human use.

2-(Thiophen-2-yl)pyridine|CS-W013265

Structure of 3319-99-1

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General Information

  • CAS No. 3319-99-1
  • Cat. No. CS-W013265
  • Purity ≥97%
  • MDL No. MFCD00044441
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₇NS
  • Molecular Weight 161.22
  • Synonym(s) 2-(2-Thienyl)pyridine
  • SMILES C1(C2=CC=CS2)=NC=CC=C1

Description

2-(Thiophen-2-yl)pyridine features a fused heteroaromatic system combining thiophene and pyridine rings, delivering enhanced electron density at the pyridine nitrogen. This structural motif enables strong coordination to transition metals, making it valuable in catalytic ligand design. The molecule exhibits bench-stable handling and good solubility in common organic solvents, facilitating integration into synthetic workflows.

Application

2-(Thiophen-2-yl)pyridine serves as a versatile heterocyclic building block in synthetic organic chemistry, enabling efficient construction of biologically relevant scaffolds. Its dual aromatic system imparts enhanced stability and favorable electronic properties, facilitating metal-catalyzed coupling reactions such as Suzuki-Miyaura and Stille couplings. The molecule exhibits excellent functional group tolerance and bench stability, making it well-suited for iterative synthesis in medicinal chemistry and materials science applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   12.89
  • LogP   2.8101
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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