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CS-W001157 4
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5-Fluoro-2-methylbenzoic acid

  • CAS No. 33184-16-6

  • Cat. No. CS-W020687
  • Purity≥97%
  • MDL No.MFCD00042294

*For research and further manufacturing use only, not for direct human use.

5-Fluoro-2-methylbenzoic acid|CS-W020687

Structure of 33184-16-6

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General Information

  • CAS No. 33184-16-6
  • Cat. No. CS-W020687
  • Purity ≥97%
  • MDL No. MFCD00042294
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₇FO₂
  • Molecular Weight 154.14
  • Synonym(s) 3-Fluoro-6-methylbenzoic acid; 5-Fluoro-o-toluic acid; 5-Fluoro-o-toluic acid (COOH=1)
  • SMILES O=C(O)C1=CC(F)=CC=C1C

Description

Ethylenediaminetetraacetic acid is used in the treatment of lead poisoning, brain damage, cancer, rheumatoid arthritis, osteoarthritis, an eye condition called macular degeneration, diabetes, Alzheimer's disease, multiple sclerosis and Parkinson's disease. It acts as a chelating agent and used for the preparation of many solutions including DNA loading dye and resuspension buffer which is isolation of plasmid.

Application

5-Fluoro-2-methylbenzoic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its ortho-methyl and meta-fluoro substituents provide enhanced metabolic stability and modulate electronic properties for target engagement. The carboxylic acid group facilitates direct coupling reactions and derivatization, while the molecule exhibits excellent bench stability and compatibility with standard purification protocols.

Synthesis

  • Route1
    • null|null
      124-38-9
    • ~60%
    • In-stock
      5-Fluoro-2-methylbenzoic acid|CS-W020687
      33184-16-6

    References

    • ALANTOS PHARMACEUTICALS, INC. Patent: WO2006/116157 A2, 2006 ; Location in patent: Page/Page column 83 ; WO 2006/116157 A2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   1.83232
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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