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Structure of 331777-85-6
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5-Bromo-2,3,3-trimethyl-3H-pyrrolo[2,3-b]pyridine features a sterically hindered pyrrolopyridine core with a bromine substituent at the 5-position, enabling direct functionalization in transition-metal-catalyzed cross-coupling reactions. The trimethyl groups enhance solubility and stability under standard reaction conditions. This scaffold serves as a robust building block for synthesizing complex heterocyclic systems in medicinal chemistry and materials science.
5-Bromo-2,3,3-trimethyl-3H-pyrrolo[2,3-b]pyridine serves as a versatile building block in heterocyclic synthesis, enabling palladium-catalyzed cross-coupling reactions due to its stable bromo functionality. The trimethyl substitution enhances steric protection and bench stability, while the pyrrolo[2,3-b]pyridine core provides a rigid, electron-deficient scaffold suitable for further functionalization. Its predictable reactivity facilitates integration into medicinal chemistry programs and API intermediate development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: