2-Bromo-1,1-dimethoxypropane

Name: 2-Bromo-1,1-dimethoxypropane
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

SDS

CAS No. 33170-72-8
Cat. No. CS-W017071
Purity≥95%
MDL No.MFCD11505877

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HazMat Fee

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Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

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Description

2-Bromo-1,1-dimethoxypropane serves as a selective alkylating agent featuring a reactive bromide and two methoxy groups that stabilize the adjacent carbon. This configuration enables efficient coupling in nucleophilic substitution reactions under mild conditions. The molecule’s bench-stable nature supports reliable handling in synthetic workflows involving carbonyl derivatives or heteroatom nucleophiles.

Application

2-Bromo-1,1-dimethoxypropane serves as a reliable alkylating agent for the selective introduction of propyl groups under mild conditions. Its dimethoxy protection stabilizes the carbonyl equivalent, enhancing bench stability and minimizing side reactions. The molecule facilitates efficient nucleophilic substitution with amines, thiols, and enolates, enabling straightforward access to functionalized intermediates in medicinal chemistry and process synthesis.

General Information

CAS No. 33170-72-8
Cat. No. CS-W017071
Purity ≥95%
MDL No. MFCD11505877
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₁₁BrO₂
Molecular Weight 183.04
Synonym(s) None
SMILES CC(Br)C(OC)OC

Computational Chemistry Data

TPSA 18.46
LogP 1.3887
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 3

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Similar Products

Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Fatty chain compounds

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