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CS-W001157 4
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1H-Benzo[d]imidazole-2-carbaldehyde

  • CAS No. 3314-30-5

  • Cat. No. CS-W004873
  • Purity≥95%
  • MDL No.MFCD00228045

*For research and further manufacturing use only, not for direct human use.

1H-Benzo[d]imidazole-2-carbaldehyde|CS-W004873

Structure of 3314-30-5

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General Information

  • CAS No. 3314-30-5
  • Cat. No. CS-W004873
  • Purity ≥95%
  • MDL No. MFCD00228045
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₆N₂O
  • Molecular Weight 146.15
  • Synonym(s) 1H-Benzimidazole-2-carboxaldehyde
  • SMILES O=CC1=NC2=CC=CC=C2N1

Description

1H-Benzo[d]imidazole-2-carbaldehyde features a rigid heteroaromatic core with a reactive aldehyde group at the 2-position, enabling direct incorporation into diverse molecular architectures. This bench-stable compound serves as a key scaffold for synthesizing bioactive imidazoles, ligands, and functional materials through efficient condensation or coupling reactions under standard conditions.

Application

1H-Benzo[d]imidazole-2-carbaldehyde serves as a versatile building block for heterocyclic synthesis, enabling efficient access to biologically relevant scaffolds. Its aldehyde functionality facilitates nucleophilic addition, reductive amination, and Ugi-type coupling reactions with high reliability. The molecule exhibits excellent bench stability and compatibility with common functional groups, supporting straightforward purification and integration into multi-step synthetic sequences.

Synthesis

  • Route1

    References

    • Dubey; Kumar, C. Ravi; Babu, Balaji Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2003 , vol. 42, # 12 p. 3128 - 3130
  • Route2

    References

    • Journal of the Indian Chemical Society, , vol. 59, # 3 p. 349 - 351
  • Route3
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      95-54-5
    • ~%
    • In-stock
      1H-Benzo[d]imidazole-2-carbaldehyde|CS-W004873
      3314-30-5

    References

    • Chemische Berichte, , vol. 89, p. 689,691

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   45.75
  • LogP   1.3754
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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