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CS-W001157 4
Total: USD 88.00

Alloc-Val-Ala-OH

  • CAS No. 330970-70-2

  • Cat. No. CS-0112535
  • Purity≥95%
  • MDL No.MFCD28387723

*For research and further manufacturing use only, not for direct human use.

Alloc-Val-Ala-OH|CS-0112535

Structure of 330970-70-2

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General Information

  • CAS No. 330970-70-2
  • Cat. No. CS-0112535
  • Purity ≥95%
  • MDL No. MFCD28387723
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₂₀N₂O₅
  • Molecular Weight 272.30
  • Synonym(s) ((Allyloxy)carbonyl)-L-valyl-L-alanine
  • SMILES OC([C@H](C)NC([C@H](C(C)C)NC(OCC=C)=O)=O)=O

Description

Alloc-Val-Ala-OH is a protected tripeptide building block featuring an Alloc (allyloxycarbonyl) group at the N-terminus and a C-terminal hydroxyl. This configuration enables orthogonal deprotection strategies in peptide synthesis, offering enhanced control during sequential coupling steps. The Val-Ala sequence provides a stable, sterically defined scaffold suitable for solid-phase and solution-phase applications.

Application

Alloc-Val-Ala-OH serves as a protected dipeptide building block for peptide synthesis, enabling efficient incorporation of valine and alanine residues with orthogonal protection. The allyloxycarbonyl (Alloc) group provides stable, acid-labile N-terminal protection compatible with standard coupling protocols and selective removal via palladium-catalyzed deprotection. Its bench-stable form facilitates handling, purification, and use in both solution-phase and solid-phase workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

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Computational Chemistry Data

  • TPSA   104.73
  • LogP   0.5125
  • H_Acceptors   4
  • H_Donors   3
  • Rotatable_Bonds   7

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