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Structure of 33094-66-5
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2-Nitrobenzofuran is a heterocyclic compound featuring a nitro group at the 2-position of the benzofuran scaffold. This electron-deficient system enhances reactivity in transition metal-catalyzed couplings and serves as a key building block in synthetic medicinal chemistry. The fused ring structure imparts planarity and rigidity, supporting applications in photophysical studies and materials science.
2-Nitrobenzofuran serves as a versatile building block in heterocyclic synthesis, enabling direct functionalization at the C3 position via electrophilic substitution or transition-metal-catalyzed coupling. Its electron-deficient aromatic system enhances reactivity in Suzuki-Miyaura and Stille reactions, while the nitro group provides a handle for selective reduction to an amino derivative. The compound exhibits good bench stability and facilitates efficient purification by column chromatography, making it well-suited for iterative synthesis of bioactive scaffolds and pharmaceutical intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: