4-Bromo-3-methylisoxazol-5-amine

Name: 4-Bromo-3-methylisoxazol-5-amine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 33084-49-0
Cat. No. CS-0437401
Purity≥98%
MDL No.MFCD09038913

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4-Bromo-3-methylisoxazol-5-amine|CS-0437401

Structure of 33084-49-0

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 33084-49-0
Cat. No. CS-0437401
Purity ≥98%
MDL No. MFCD09038913
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₄H₅BrN₂O
Molecular Weight 177.00
Synonym(s) 5-AMINO-4-BROMO-3-METHYLISOXAZOLE
SMILES NC1=C(Br)C(C)=NO1

Description

4-Bromo-3-methylisoxazol-5-amine features a brominated isoxazole core with a methyl substituent and a primary amine at the 5-position, offering a versatile scaffold for medicinal chemistry. The electron-deficient heterocycle enables efficient coupling reactions, while the amine group facilitates derivatization under standard conditions. This bench-stable compound serves as a key building block in targeted synthesis workflows.

Application

4-Bromo-3-methylisoxazol-5-amine serves as a versatile building block for the synthesis of bioactive heterocycles, particularly in medicinal chemistry and agrochemical research. Its bromine substituent enables efficient palladium-catalyzed cross-coupling reactions, while the pendant amine facilitates derivatization via acylation or reductive alkylation. The molecule exhibits good bench stability and is compatible with common protecting group strategies, making it well-suited for modular scaffold construction.

Synthesis

Route1
- In-stock
  
  14678-02-5
- ~88%
- In-stock
  
  33084-49-0
References
- Texas Biotechnology Corp. Patent: US6342610 B2, 2002 ; Location in patent: Page column 141 ; US 6342610 B2
Route2
- In-stock
  
  14678-02-5
- In-stock
  
  128-08-5
- ~87%
- In-stock
  
  33084-49-0
References
- Immunopharmaceutics, Inc. Patent: US5514691 A1, 1996 ;

Safety Information

Download SDS

GHS Pictogram : N/A	GHS No : N/A
Signal Word : N/A	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 52.05
LogP 1.32772
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 0

Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Isoxazole compounds

Key Words

4-Bromo-3-methylisoxazol-5-amine sigma4-Bromo-3-methylisoxazol-5-amine manufacturer4-Bromo-3-methylisoxazol-5-amine price4-Bromo-3-methylisoxazol-5-amine structure4-Bromo-3-methylisoxazol-5-amine SDSbuy 4-Bromo-3-methylisoxazol-5-amine4-Bromo-3-methylisoxazol-5-amine supplier4-Bromo-3-methylisoxazol-5-amine uses4-Bromo-3-methylisoxazol-5-amine molecular weightprice of 4-Bromo-3-methylisoxazol-5-amine4-Bromo-3-methylisoxazol-5-amine chemical name formula of 4-Bromo-3-methylisoxazol-5-amine

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

4-Bromo-3-methylisoxazol-5-amine

CAS No. 33084-49-0

Recommended Products