Lot numbers can be found on the outside label of a product:
H-Phe-Leu-OH
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CAS No. 3303-55-7
- Cat. No. CS-0077187
- Purity≥95%
- MDL No.MFCD00038297
*For research and further manufacturing use only, not for direct human use.
Structure of 3303-55-7
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General Information
- CAS No. 3303-55-7
- Cat. No. CS-0077187
- Purity ≥95%
- MDL No. MFCD00038297
- Storage 4°C
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₁₅H₂₂N₂O₃
- Molecular Weight 278.35
- Synonym(s) L-Phenylalanyl-L-leucine; Phe-Leu
- SMILES CC(C)C[C@@H](C(O)=O)NC([C@H](CC1=CC=CC=C1)N)=O
Description
L-Phenylalanyl-L-leucine is a dipeptide featuring a phenylalanine residue linked via a peptide bond to leucine, offering enhanced stability and solubility in aqueous systems. This dipeptide serves as a key building block in peptide synthesis and bioactive compound development, particularly where hydrophobic character and metabolic resistance are required.
Application
L-Phenylalanyl-L-leucine serves as a stable dipeptide building block for peptide synthesis, offering predictable coupling efficiency and orthogonal protection compatibility. Its hydrophobic side chains enhance solubility in organic media and facilitate purification via standard chromatographic methods. Functions reliably in solid-phase and solution-phase workflows, enabling access to bioactive peptide sequences with high fidelity.
Synthesis
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Route1
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61-90-5 -
81917-69-3 - ~87%
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In-stock
3303-55-7
References
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Butula, I.; Zorc, B.; Ljubic, M.; Karlovic, G. Synthesis, 1983 , # 4 p. 327 - 329
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Route2
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In-stock
4313-73-9 - ~83%
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In-stock
3303-55-7
References
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Patel, Ramesh N.; Nanduri, Venkata; Brzozowski, David; McNamee, Clyde; Banerjee, Amit Advanced Synthesis and Catalysis, 2003 , vol. 345, # 6-7 p. 830 - 834
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Route3
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61-90-5
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3081-24-1 - ~%
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In-stock
3303-55-7
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In-stock
2862-51-3
References
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Chemical Communications, , vol. 46, # 4 p. 580 - 582
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Safety Information
Download SDS|
GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Quality Control
Computational Chemistry Data
- TPSA 92.42
- LogP 1.1719
- H_Acceptors 3
- H_Donors 3
- Rotatable_Bonds 7
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Key Words
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