Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

5-Bromo-3-chlorotoluene

  • CAS No. 329944-72-1

  • Cat. No. CS-0030598
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

5-Bromo-3-chlorotoluene|CS-0030598

Structure of 329944-72-1

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 329944-72-1
  • Cat. No. CS-0030598
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆BrCl
  • Molecular Weight 205.48
  • Synonym(s) Benzene, 1-bromo-3-chloro-5-methyl-
  • SMILES CC1=CC(Cl)=CC(Br)=C1

Description

5-Bromo-3-chlorotoluene features a methyl group flanked by bromo and chloro substituents at meta positions, enabling selective functionalization in cross-coupling reactions. This electron-deficient aromatic scaffold offers enhanced reactivity in palladium-catalyzed transformations while maintaining bench-stable handling characteristics.

Application

5-Bromo-3-chlorotoluene serves as a versatile building block in cross-coupling chemistry, enabling efficient palladium-catalyzed transformations such as Suzuki-Miyaura and Stille reactions. The ortho-halogenated aryl scaffold exhibits excellent bench stability and compatibility with diverse functional groups, facilitating the synthesis of complex biaryls and substituted heterocycles. Its defined substitution pattern supports predictable regioselective reactivity, making it ideal for pharmaceutical intermediates and materials science applications.

Synthesis

  • Route1

    References

    • Gerritz, Samuel; Shi, Shuhao; Zhu, Shirong Patent: US2006/287287 A1, 2006 ; Location in patent: Page/Page column 18 ; US 20060287287 A1
  • Route2

    References

    • Romines, Karen R.; Freeman, George A.; Schaller, Lee T.; Cowan, Jill R.; Gonzales, Steve S.; Tidwell, Jeffrey H.; Andrews III, Clarence W.; Stammers, David K.; Hazen, Richard J.; Ferris, Robert G.; Short, Steven A.; Chan, Joseph H.; Boone, Lawrence R. Journal of Medicinal Chemistry, 2006 , vol. 49, # 2 p. 727 - 739
  • Route3

    References

    • Murphy, Jaclyn M.; Liao, Xuebin; Hartwig, John F. Journal of the American Chemical Society, 2007 , vol. 129, # 50 p. 15434 - 15435

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   0
  • LogP   3.41092
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 5-Bromo-3-chlorotoluene sigma5-Bromo-3-chlorotoluene manufacturer5-Bromo-3-chlorotoluene price5-Bromo-3-chlorotoluene structure5-Bromo-3-chlorotoluene SDSbuy 5-Bromo-3-chlorotoluene5-Bromo-3-chlorotoluene supplier5-Bromo-3-chlorotoluene uses5-Bromo-3-chlorotoluene molecular weightprice of 5-Bromo-3-chlorotoluene5-Bromo-3-chlorotoluene chemical name formula of 5-Bromo-3-chlorotoluene
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label