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CS-W001157 4
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2-(2-Pyridyl)benzoxazole

  • CAS No. 32959-62-9

  • Cat. No. CS-0087384
  • Molecule weightNone
  • Purity≥97%
  • MDL No.MFCD00569582

*For research and further manufacturing use only, not for direct human use.

2-(2-Pyridyl)benzoxazole|CS-0087384

Structure of 32959-62-9

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General Information

  • CAS No. 32959-62-9
  • Cat. No. CS-0087384
  • Purity ≥97%
  • MDL No. MFCD00569582
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₈N₂O
  • Molecular Weight None
  • Synonym(s) None
  • SMILES C12=CC=CC=C1N=C(C3=CC=CC=N3)O2

Description

2-(2-Pyridyl)benzoxazole is a heterocyclic scaffold featuring fused benzoxazole and pyridine rings, offering enhanced electron-deficient character and planarity. This rigid, polar structure facilitates π-stacking interactions and serves as a robust ligand in coordination chemistry and organic electronics.

Application

2-(2-Pyridyl)benzoxazole serves as a versatile heterocyclic building block in medicinal chemistry and materials science, enabling efficient construction of fused polycyclic scaffolds. Its rigid, planar structure enhances π-stacking interactions, while the pyridyl and oxazole moieties provide sites for metal coordination and functionalization. The compound exhibits excellent bench stability and facilitates straightforward derivatization via electrophilic substitution or transition-metal-catalyzed coupling reactions, making it valuable for catalyst ligand design and the synthesis of advanced organic semiconductors.

Synthesis

  • Route1

    References

    • Journal of the American Chemical Society, , vol. 129, # 41 p. 12404 - 12405
  • Route2
    • In-stock
      Picolinaldehyde|CS-W007336
      1121-60-4
    • null|null
      95-55-6
    • ~71%
    • In-stock
      2-(2-Pyridyl)benzoxazole|CS-0087384
      32959-62-9

    References

    • Tetrahedron Letters, , vol. 52, # 17 p. 2128 - 2131
  • Route3
    • N-(2-Iodophenyl)picolinamide|CS-0290746
      794574-51-9
    • ~74%
    • In-stock
      2-(2-Pyridyl)benzoxazole|CS-0087384
      32959-62-9

    References

    • Tetrahedron, , vol. 69, # 14 p. 2920 - 2926

Safety Information

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GHS Pictogram : N/A
GHS No : N/A
Signal Word : N/A
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

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Computational Chemistry Data

  • TPSA   38.92
  • LogP   2.8898
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   1

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