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CS-W001157 4
Total: USD 88.00

1-Chloromethyl-3,5-dichlorobenzene

  • CAS No. 3290-06-0

  • Cat. No. CS-0020159
  • Purity≥98%
  • MDL No.MFCD00060278

*For research and further manufacturing use only, not for direct human use.

1-Chloromethyl-3,5-dichlorobenzene|CS-0020159

Structure of 3290-06-0

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General Information

  • CAS No. 3290-06-0
  • Cat. No. CS-0020159
  • Purity ≥98%
  • MDL No. MFCD00060278
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅Cl₃
  • Molecular Weight 195.47
  • Synonym(s) 3,5-Dichlorobenzyl chloride
  • SMILES ClCC1=CC(Cl)=CC(Cl)=C1

Description

1-Chloromethyl-3,5-dichlorobenzene features a reactive benzyl chloride group flanked by two electron-withdrawing chlorine atoms, enhancing electrophilicity and stability. This configuration enables efficient coupling in nucleophilic substitution reactions, particularly in the synthesis of functionalized aromatic intermediates for pharmaceuticals and agrochemicals.

Application

1-Chloromethyl-3,5-dichlorobenzene serves as a versatile building block in synthetic organic chemistry, enabling efficient introduction of a reactive benzyl chloride handle into complex architectures. Its trifunctional substitution pattern provides enhanced regiochemical control and stability under standard reaction conditions, facilitating downstream transformations such as nucleophilic substitutions, Suzuki couplings, and heterocycle construction. The molecule exhibits excellent bench stability and is readily purified by distillation or chromatography, making it ideal for multi-step synthesis workflows in medicinal chemistry and materials science applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501

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Computational Chemistry Data

  • TPSA   0
  • LogP   3.7322
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   1

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