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CS-W001157 4
Total: USD 88.00

tert-Butyl ethyl propanedioate

  • CAS No. 32864-38-3

  • Cat. No. CS-0015722
  • Purity≥95%
  • MDL No.MFCD00009193

*For research and further manufacturing use only, not for direct human use.

tert-Butyl ethyl propanedioate|CS-0015722

Structure of 32864-38-3

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General Information

  • CAS No. 32864-38-3
  • Cat. No. CS-0015722
  • Purity ≥95%
  • MDL No. MFCD00009193
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₆O₄
  • Molecular Weight 188.22
  • Synonym(s) tert-Butyl ethyl malonate
  • SMILES O=C(OC(C)(C)C)CC(OCC)=O

Description

tert-Butyl ethyl malonate was used in the synthesis of polar ester-functionalized aliphatic polysulfone with remarkable thermal stability.

Application

tert-Butyl ethyl propanedioate serves as a versatile synthon in synthetic organic chemistry, enabling efficient access to substituted malonate derivatives through standard alkylation and hydrolysis protocols. Its tert-butyl ester group provides enhanced bench stability and facilitates straightforward purification via acid-mediated cleavage. The molecule functions effectively in Michael additions, heterocycle synthesis, and as a building block for bioactive scaffolds requiring α-dicarbonyl motifs.

Synthesis

  • Route1
    • In-stock
      3-Ethoxy-3-oxopropanoic acid|CS-0016016
      1071-46-1
    • null|null
      75-65-0
    • ~99%
    • In-stock
      tert-Butyl ethyl propanedioate|CS-0015722
      32864-38-3

    References

    • Nahmany, Moshe; Melman, Artem Organic Letters, 2001 , vol. 3, # 23 p. 3733 - 3735 Title/Abstract Full Text View citing articles Show Details Shelkov, Rimma; Nahmany, Moshe; Melman, Artem Journal of Organic Chemistry, 2002 , vol. 67, # 25 p. 8975 - 8982
  • Route2
    • null|null
      36239-09-5
    • null|null
      75-65-0
    • ~84%
    • In-stock
      tert-Butyl ethyl propanedioate|CS-0015722
      32864-38-3

    References

    • Shang, Rui; Ji, Dong-Sheng; Chu, Ling; Fu, Yao; Liu, Lei Angewandte Chemie - International Edition, 2011 , vol. 50, # 19 p. 4470 - 4474
  • Route3
    • In-stock
      3-Ethoxy-3-oxopropanoic acid|CS-0016016
      1071-46-1
    • null|null
      115-11-7
    • ~78%
    • In-stock
      tert-Butyl ethyl propanedioate|CS-0015722
      32864-38-3

    References

    • Hediger, Mark E. Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 18 p. 4995 - 5010

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   52.6
  • LogP   1.2813
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   3

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