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CS-W001157 4
Total: USD 88.00

4-tert-Butylphenylacetic acid

  • CAS No. 32857-63-9

  • Cat. No. CS-0130494
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-tert-Butylphenylacetic acid|CS-0130494

Structure of 32857-63-9

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General Information

  • CAS No. 32857-63-9
  • Cat. No. CS-0130494
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₆O₂
  • Molecular Weight 192.25
  • Synonym(s) Butylphenylessigsureca
  • SMILES O=C(CC1=CC=C(C=C1)C(C)(C)C)O

Description

4-tert-Butylphenylacetic acid features a sterically hindered tert-butyl group that enhances stability and modulates reactivity. This aromatic carboxylic acid integrates readily into synthetic routes requiring bulky, electron-donating substituents. Its bench-stable nature supports reliable handling in process development workflows.

Application

4-tert-Butylphenylacetic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive molecules through standard functional group transformations. Its tert-butyl substituent provides steric bulk and metabolic stability, while the carboxylic acid functionality facilitates amide coupling, esterification, and derivatization under mild conditions. The compound exhibits excellent bench stability and ease of purification, making it well-suited for high-throughput screening campaigns and scale-up applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   2.6112
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   2

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