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Structure of 328-67-6
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3-Bromo-5-(trifluoromethyl)benzoic acid features a strategically positioned bromine atom and a strongly electron-withdrawing trifluoromethyl group, enhancing its utility in cross-coupling reactions. The carboxylic acid functionality enables direct derivatization or salt formation, while the halogenated aromatic core provides high stability under standard bench conditions. This compound serves as a key building block for bioactive molecules and functional materials.
3-Bromo-5-(trifluoromethyl)benzoic acid serves as a versatile building block for the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its bromo and trifluoromethyl groups enable diverse cross-coupling reactions, while the carboxylic acid facilitates direct derivatization or coupling protocols. The compound exhibits excellent bench stability and is readily purified by recrystallization, making it well-suited for iterative synthetic workflows in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: