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CS-W001157 4
Total: USD 88.00

Bis(vinylsulfonyl)methane

  • CAS No. 3278-22-6

  • Cat. No. CS-W010594
  • Purity≥97%
  • MDL No.MFCD03265421

*For research and further manufacturing use only, not for direct human use.

Bis(vinylsulfonyl)methane|CS-W010594

Structure of 3278-22-6

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General Information

  • CAS No. 3278-22-6
  • Cat. No. CS-W010594
  • Purity ≥97%
  • MDL No. MFCD03265421
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₈O₄S₂
  • Molecular Weight 196.24
  • Synonym(s) 1,1'-[methylenebis(sulfonyl)]bisethene
  • SMILES O=S(CS(=O)(C=C)=O)(C=C)=O

Description

Bis(vinylsulfonyl)methane features two vinylsulfonyl groups flanking a central methylene unit, enabling efficient conjugate addition reactions. This bifunctional electrophile integrates readily into polymer backbones and bioconjugation workflows under mild conditions. The molecule demonstrates robust stability in aqueous environments and tolerates a range of reaction pH levels.

Application

Bis(vinylsulfonyl)methane serves as a versatile bifunctional crosslinking agent, enabling efficient conjugation of biomolecules and polymers through nucleophilic addition at physiological pH. Its dual vinylsulfonyl groups exhibit high reactivity toward amines and thiols, facilitating site-specific labeling and immobilization. The compound demonstrates excellent bench stability, ease of purification, and compatibility with aqueous and organic solvents, making it well-suited for protein modification, bioconjugation workflows, and the synthesis of functionalized materials.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06,GHS08
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H315-H319-H340
Precautionary Statements : P264-P280-P405-P501

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Computational Chemistry Data

  • TPSA   68.28
  • LogP   0.0605
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   4

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