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CS-W001157 4
Total: USD 88.00

(S)-2-Amino-2-(p-tolyl)ethanol

  • CAS No. 327183-90-4

  • Cat. No. CS-0037480
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(S)-2-Amino-2-(p-tolyl)ethanol|CS-0037480

Structure of 327183-90-4

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General Information

  • CAS No. 327183-90-4
  • Cat. No. CS-0037480
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₃NO
  • Molecular Weight 151.21
  • Synonym(s) (2S)-2-AMino-2-(4-Methylphenyl)ethan-1-ol
  • SMILES CC1=CC=C([C@H](N)CO)C=C1

Description

(S)-2-Amino-2-(p-tolyl)ethanol is a chiral building block featuring a pendant para-tolyl group and a primary amine, enabling selective functionalization in asymmetric synthesis. This bench-stable, moisture-tolerant scaffold integrates readily into pharmaceutical intermediates and ligands, offering high stereocontrol in catalytic transformations.

Application

(S)-2-Amino-2-(p-tolyl)ethanol serves as a versatile chiral building block in synthetic organic chemistry, enabling the construction of pharmaceutically relevant scaffolds. Its well-defined stereochemistry and bench-stable nature facilitate reliable incorporation into diverse transformations, including amide coupling, cyclization, and metal-catalyzed cross-couplings. The para-tolyl group provides enhanced stability and compatibility with standard purification methods, making it ideal for use in medicinal chemistry campaigns and process development workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   46.25
  • LogP   0.98712
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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