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Structure of 326476-49-7
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This pyridine derivative features a strategically positioned trifluoromethyl group enhancing electron-withdrawing character and a chloro substituent enabling downstream functionalization. The aminomethyl handle delivers a reactive site for conjugation, while the hydrochloride salt ensures improved solubility and stability under standard handling conditions.
2-(Aminomethyl)-3-chloro-5-(trifluoromethyl)pyridine Hydrochloride serves as a versatile building block for medicinal chemistry, enabling efficient access to substituted pyridine scaffolds. The chloro and trifluoromethyl groups provide orthogonal reactivity for cross-coupling and nucleophilic substitution, while the protonated aminomethyl functionality enhances solubility and facilitates downstream derivatization. This stable, bench-ready intermediate supports diverse functionalization in API development workflows.
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GHS Pictogram :
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GHS No : GHS05,GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H315-H318-H335
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Precautionary Statements : P264-P270-P330-P405-P501
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Lot numbers can be found on the outside label of a product: