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CS-W001157 4
Total: USD 88.00

3-Chloro-2-methylphenol

  • CAS No. 3260-87-5

  • Cat. No. CS-W019378
  • Purity≥98%
  • MDL No.MFCD00079738

*For research and further manufacturing use only, not for direct human use.

3-Chloro-2-methylphenol|CS-W019378

Structure of 3260-87-5

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General Information

  • CAS No. 3260-87-5
  • Cat. No. CS-W019378
  • Purity ≥98%
  • MDL No. MFCD00079738
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₇ClO
  • Molecular Weight 142.58
  • Synonym(s) Phenol, 3-chloro-2-methyl- (9CI)
  • SMILES C1=C(C(=C(C=C1)Cl)C)O

Description

3-Chloro-2-methylphenol is a chlorinated cresol derivative featuring a methyl group ortho to the hydroxyl function. This structural arrangement imparts enhanced reactivity in electrophilic substitution and improved solubility in organic media compared to unsubstituted phenols. The compound serves as a key intermediate in agrochemical synthesis and specialty polymer formulations.

Application

3-Chloro-2-methylphenol serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling regioselective functionalization via its ortho-methyl and meta-chloro substituents. The phenolic hydroxyl group facilitates direct coupling reactions and derivatization, while the chloro and methyl groups provide orthogonal handles for cross-coupling, electrophilic substitution, and further functionalization. Bench-stable and amenable to purification by distillation or recrystallization, it functions reliably in standard synthetic workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07,GHS09
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H319-H411
Precautionary Statements : P264-P270-P273-P280-P330-P391-P501

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Computational Chemistry Data

  • TPSA   20.23
  • LogP   2.35402
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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