5-Fluoro-2-methylphenylhydrazine hydrochloride

Name: 5-Fluoro-2-methylphenylhydrazine hydrochloride
Brand: ChemScene
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CAS No. 325-50-8
Cat. No. CS-W017389
Purity≥98%
MDL No.MFCD00053032

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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5-Fluoro-2-methylphenylhydrazine hydrochloride|CS-W017389

Structure of 325-50-8

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Description

5-Fluoro-2-methylphenylhydrazine hydrochloride features a fluorinated aromatic ring paired with a methyl group and a hydrazine functionality, enabling selective coupling in heterocyclic synthesis. This bench-stable derivative facilitates efficient access to biologically relevant scaffolds under standard conditions.

Application

5-Fluoro-2-methylphenylhydrazine hydrochloride serves as a versatile building block for heterocyclic synthesis, enabling efficient access to substituted pyrazoles and other nitrogen-containing scaffolds. Its stability under standard bench conditions and compatibility with common coupling protocols facilitate straightforward incorporation into medicinal chemistry campaigns. The ortho-fluoro and methyl substituents provide predictable electronic modulation and enhanced functional group tolerance during downstream transformations.

General Information

CAS No. 325-50-8
Cat. No. CS-W017389
Purity ≥98%
MDL No. MFCD00053032
Storage 4°C, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₁₀ClFN₂
Molecular Weight None
Synonym(s) (5-fluoro-2-methylphenyl)diazanium chloride
SMILES CC1=C(NN)C=C(F)C=C1.Cl

Computational Chemistry Data

TPSA 38.05
LogP 1.84152
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 1

Safety Information

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GHS Pictogram : N/A	GHS No : N/A
Signal Word : N/A	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

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Other Classifications

Building Blocks Functional Group Hydrazine

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

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5-Fluoro-2-methylphenylhydrazine hydrochloride

CAS No. 325-50-8

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