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CS-W001157 4
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3-Amino-2,2-dimethylpropanamide

  • CAS No. 324763-51-1

  • Cat. No. CS-W003343
  • Purity≥97%
  • MDL No.MFCD06797568

*For research and further manufacturing use only, not for direct human use.

3-Amino-2,2-dimethylpropanamide|CS-W003343

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General Information

  • CAS No. 324763-51-1
  • Cat. No. CS-W003343
  • Purity ≥97%
  • MDL No. MFCD06797568
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₂N₂O
  • Molecular Weight 116.16
  • Synonym(s) Propanamide, 3-amino-2,2-dimethyl-
  • SMILES O=C(N)C(C)(C)CN

Description

3-Amino-2,2-dimethylpropanamide features a sterically hindered tertiary carbon center paired with a primary amine and amide functional group, enabling robust participation in peptide coupling and conjugation workflows. This bench-stable derivative delivers efficient incorporation into bioconjugates and polymer architectures under standard conditions.

Application

3-Amino-2,2-dimethylpropanamide serves as a valuable building block in peptide synthesis and medicinal chemistry, offering a sterically hindered aliphatic amine with enhanced solubility and stability. Its N–H functionality enables straightforward derivatization via acylation or coupling reactions, while the tert-butyl-like quaternary carbon minimizes undesired side reactions. The compound functions effectively as a synthetic equivalent for branched-chain amino acid motifs and facilitates the construction of complex scaffolds under standard conditions.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   69.11
  • LogP   -0.5434
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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