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Structure of 32431-84-8
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3-Fluorothiophene-2-carboxylic acid integrates a fluorine atom at the 3-position and a carboxylic acid group at the 2-position of a thiophene core. This combination imparts enhanced electron-withdrawing character and improved metabolic stability, making it valuable for constructing bioactive heterocycles in medicinal chemistry and materials science applications.
3-Fluorothiophene-2-carboxylic acid serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling direct incorporation of fluorinated thiophene motifs into bioactive molecules. Its carboxylic acid functionality facilitates straightforward amide, ester, and acyl chloride derivatization, while the fluorine substituent enhances metabolic stability and modulates electronic properties. The compound exhibits good bench stability and is compatible with standard coupling protocols, making it well-suited for high-throughput synthesis and scale-up applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: